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Randomised Evaluation of COVID-19 therapy (RECOVERY), a clinical based trial in UK found that Dexamethasone, a steroid-based drug, is effective in reducing mortality due to severe COVID-19.
In the trial, around 2,100 patients were randomly assigned to get the steroid. This was compared with over 4,300 patients who did not get it.
It has reduced deaths of patients on ventilators by one-third and patients on oxygen by one-fifth.
The drug is an inexpensive and a commonly available drug. It is widely used to treat diseases like lupus, arthritis, asthma and some skin conditions.
It appears to reduce inflammation caused by the immune system, protecting the tissues.
The trials also find that Hydroxychloroquine is not effective in reducing mortality.